Search results for "Human breast milk"

showing 3 items of 3 documents

Transfer of aciclovir from plasma to human breast milk.

2011

Aciclovir (CAS 59277-89-3) is frequently used in herpes simplex virus diseases, but administration to lactating women occurs only rarely. Therefore, information about the pharmacokinetics of aciclovir in human breast milk is limited. The concentration in breast milk is 2 to 3 fold increased compared to plasma. The reason for this increase is unknown until now. An active transport mechanism has been assumed. The aim of this study was to prove whether the higher concentration of aciclovir in human breast milk is due to only a passive transfer. Two chambers separated by a semipermeable membrane were used. The first chamber contained plasma with aciclovir, the second chamber breast milk without…

AdultMilk HumanChemistryAcyclic nucleosidevirus diseasesHuman metabolismAcyclovirPharmacologyBreast milkmedicine.disease_causeAntiviral AgentsDiffusionHerpes simplex virusPharmacokineticsDrug DiscoveryBlood plasmaImmunologymedicineHumansFemaleAciclovirHuman breast milkmedicine.drugArzneimittel-Forschung
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Vitamin E as an IgE inhibitor: stability during cold storage of human milk

2008

Human breast milk is recommended as the unique food for neonates based on its known properties. When the production of milk by themother is not sufcient or the mother is not able to feed her child for professional reasons, milk banks or the mothers’ practice ofcollecting their own milk are the existing alternatives for breast-feeding. In both situations cold storage (refrigeration or freezing) can beused in neonatal units, at home and in human milk banks

Nutrition and Dieteticsbiologybusiness.industryVitamin Emedicine.medical_treatmentfood and beveragesMedicine (miscellaneous)Cold storageImmunoglobulin Efluids and secretionsbiology.proteinMedicineFood scienceMilk BanksbusinessHuman breast milkProceedings of the Nutrition Society
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Evaluation of mycotoxins and their metabolites in human breast milk using liquid chromatography coupled to high resolution mass spectrometry

2014

Humans can be exposed to mycotoxins through the food chain. Mycotoxins are mainly found as contaminants in food and could be subsequently excreted via biological fluids such as urine or human breast milk in native or metabolised form. Since breast milk is usually supposed as the only food for new-borns, the occurrence of mycotoxins in thirty-five human milk samples was evaluated by a newly developed method based on QuEChERS extraction and UHPLC-HRMS detection. The method described here allows the detection of target mycotoxins in order to determine the quality of this initial feeding. The method has been fully validated, with recoveries ranging from 64% to 93% and relative standard deviatio…

Sample preparationFood ContaminationUrineBreast milkQuechersOrbitrapBiochemistryMass SpectrometryAnalytical Chemistrylaw.inventionchemistry.chemical_compoundLiquid chromatography-high resolution mass spectrometrylawPregnancyEnvironmental ChemistryHumansSample preparationMycotoxinHuman breast milkSpectroscopyChromatography High Pressure LiquidChromatographyMilk HumanChemistryHuman milkInfant Newbornfood and beveragesReproducibility of ResultsContaminationMycotoxinsOrbitrapFemaleBiomarkersAnalytica Chimica Acta
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